Flow-Mediated Vasodilation as a Diagnostic Modality for Vascular Failure
نویسندگان
چکیده
منابع مشابه
Nitroglycerine-induced vasodilation for assessment of vascular function: a comparison with flow-mediated vasodilation.
OBJECTIVE Nitroglycerine-induced vasodilation has been used as a control test for flow-mediated vasodilation (FMD) to differentiate endothelium-dependent from endothelium-independent response when evaluating endothelial function in humans. Recently, nitroglycerine-induced vasodilation has also been reported to be impaired in patients with atherosclerosis. The purpose of this study was to determ...
متن کاملFlow - Mediated Vasodilation *
Brachial arterial flow-mediated dilation (FMD), assessed by high-resolution ultrasonography, reflects endothelium-dependent vasodilator function. FMD is diminished in patients with atherosclerosis and with coronary risk factors, and improves with risk-reduction therapy. Therefore, the measurement of FMD can be a good prognostic instrument in preventive cardiology, is useful to predict short-ter...
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The epithelial sodium channel (ENaC) contributes to blood pressure homeostasis through renal salt and water transport; increases in ENaC activity increase salt and water reabsorption along the distal nephron, increasing extracellular fluid volume and blood pressure. The importance of tubular ENaC in cardiovascular homeostasis is manifested in Liddle’s disease and type I pseudohypoaldosteronism,...
متن کاملHaemoglobin and flow-mediated vasodilation.
A low [Hb] (Hb concentration) is out-balanced by peripheral vasodilation via mechanisms that are incompletely understood. Peripheral vasodilation is influenced by NO (nitric oxide) released from vascular endothelium in response to increased vessel wall shear stress, and absorption by Hb is the main mechanism by which the bioactivity of NO is disarmed. Thus we propose that graded NO absorption i...
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There is currently much research devoted to the study of vascular biology in intact humans. These efforts aim to translate findings from the basic science arena to a better understanding of the pathophysiology of atherosclerosis and its complications. Markers of vascular risk have been used as surrogate end points in treatment studies. More recently, long-term studies have emerged that speak to...
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ژورنال
عنوان ژورنال: Hypertension Research
سال: 2008
ISSN: 0916-9636,1348-4214
DOI: 10.1291/hypres.31.2105